TY - JOUR
T1 - Bacille calmette-guérin vaccination for the prevention of tuberculosis in health care workers
AU - Brewer, Timothy F.
AU - Colditz, Graham A.
N1 - Funding Information:
Financial support: This work was supported by the Centers for Disease Control and Prevention through a collaborative agreement with the Association for Schools of Public Health. T.F.B. was supported by an Alfred L. Frechette Postdoctoral Research Fellowship in Public Health from the Massachusetts Health Research Institute, Boston, and a grant from the Potts Memorial Foundation, Hudson, New York.
PY - 1995/1
Y1 - 1995/1
N2 - For 60 years vaccination with bacille Calmette-Guerin (BCG) has been used for the prevention of tuberculosis in health care workers. In1988 the U.S. Advisory Committee on ImmunizationPractices removed the category of health care worker from the list of persons for whom vaccination with BCG should be considered. Nosocomial epidemics of tuberculosis, especially those caused by multidrug-resistant strains, have led to the reconsideration of vaccination with BCG for thispopulation. We review the available studies of the efficacy of BCG vaccine in health care workers. Although the studies had too many methodological flaws to be combined in a quantitative meta-analysis, theysuggest that vaccination with BCGis effective in reducing the incidence of tuberculosis among health care workers.
AB - For 60 years vaccination with bacille Calmette-Guerin (BCG) has been used for the prevention of tuberculosis in health care workers. In1988 the U.S. Advisory Committee on ImmunizationPractices removed the category of health care worker from the list of persons for whom vaccination with BCG should be considered. Nosocomial epidemics of tuberculosis, especially those caused by multidrug-resistant strains, have led to the reconsideration of vaccination with BCG for thispopulation. We review the available studies of the efficacy of BCG vaccine in health care workers. Although the studies had too many methodological flaws to be combined in a quantitative meta-analysis, theysuggest that vaccination with BCGis effective in reducing the incidence of tuberculosis among health care workers.
UR - http://www.scopus.com/inward/record.url?scp=0028981706&partnerID=8YFLogxK
U2 - 10.1093/clinids/20.1.136
DO - 10.1093/clinids/20.1.136
M3 - Article
C2 - 7727639
AN - SCOPUS:0028981706
SN - 1058-4838
VL - 20
SP - 136
EP - 142
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 1
ER -