Axon pathfinding is an important process in the development of the nervous system. Models have been developed which describe or attempt to explain various aspects of axon pathfinding, such as axon extension, axon turning, axon guidance, interactions between axons, retinotectal mapping, and the way in which guidance cue patterns are generated in the embryo. These models generate experimentally testable predictions and also provide sophisticated frameworks from which to interpret experimental results.

Original languageEnglish
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier Ltd
Number of pages6
ISBN (Print)9780080450469
StatePublished - 2009


  • Axon guidance
  • Chemotaxis
  • Computational neuroscience
  • Computer models
  • Gradients
  • Growth cone
  • Mathematical models
  • Neural development
  • Neurite outgrowth
  • Patterning
  • Signal processing


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