Avoiding the high bonferroni penalty in genome-wide association studies

Keyphrases

• Genome-wide Association Study 100%
• Bonferroni 100%
• Permutation Test 50%
• Genetic Association Studies 50%
• Random Shuffle 50%
• Statistical Significance 25%
• Single nucleotide Polymorphism 25%
• Hypothesis Testing 25%
• Population Sample 25%
• Attractive Alternatives 25%
• Illumina 25%
• Affymetrix GeneChip 25%
• Approximation Algorithms 25%
• Genotyping Platforms 25%
• Significance Threshold 25%
• Computationally Intensive 25%
• Multiple Testing 25%
• Practical Guidelines 25%
• BeadChip 25%
• Multiple Testing Adjustment 25%
• Set-based 25%
• Statistical Theory 25%
• Best Approximation 25%
• Effective number of Tests 25%

Mathematics

• Permutation 100%
• Multiple Testing 66%
• Permutation Test 66%
• Gold Standard 33%
• Significance Test 33%
• Statistical Theory 33%
• Hypothesis Test 33%
• Best Approximation 33%

Biochemistry, Genetics and Molecular Biology

• Genome-Wide Association Study 100%
• Genetic Association Study 50%
• Single-Nucleotide Polymorphism 25%
• Genotyping 25%