Autophagy is required for the therapeutic effects of the NAD+ precursor nicotinamide in obesity-related heart failure with preserved ejection fraction

  • Mahmoud Abdellatif
  • , Francisco Vasques-Nóvoa
  • , Viktoria Trummer-Herbst
  • , Sylvère Durand
  • , Franziska Koser
  • , Moydul Islam
  • , Jihoon Nah
  • , Eun Ah Sung
  • , Ruli Feng
  • , Fanny Aprahamian
  • , Andreas Prokesch
  • , Pablo Zardoya-Laguardia
  • , Junichi Sadoshima
  • , Abhinav Diwan
  • , Wolfgang A. Linke
  • , João Pedro Ferreira
  • , Guido Kroemer
  • , Simon Sedej

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1863-1866
Number of pages4
JournalEuropean heart journal
Volume46
Issue number19
DOIs
StatePublished - May 14 2025

Keywords

  • Autophagy
  • HFpEF
  • Metabolic cardiomyopathy
  • Mitophagy
  • NAD+ metabolism
  • Obesity

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