Automatic measurement of atrial pacing thresholds in dual-chamber pacemakers: Clinical experience with atrial capture management

Johannes Sperzel, Goran Milasinovic, Timothy W. Smith, Hardwin Mead, Johan Brandt, Wesley K. Haisty, J. Russell Bailey, Marc Roelke, Jay Simonson, Jennifer Englund, Eric Farges, Steven Compton

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Background: The Medtronic EnPulse™ pacemaker incorporates the new atrial capture management (ACM) algorithm to automatically measure atrial capture thresholds and subsequently manage atrial pacing outputs. Objectives: The purpose of this study was to evaluate the clinical performance of ACM. Methods: Two hundred patients with an indication for a dual-chamber pacemaker underwent implantation. ACM thresholds and manually measured atrial pacing thresholds were assessed at follow-up visits. Clinical equivalence was defined as the ACM-measured threshold being within -0.25 V to +0.5 V of the manually measured threshold. The clinician analyzed all ACM measurements performed in-office for evidence of proarrhythmia. Results: All 200 implanted patients had a 1-month visit, and validated manual and in-office ACM threshold data were available for 123 patients. The ACM threshold was 0.595 ± 0.252 V, and the manual threshold was 0.584 ± 0.233 V. The mean difference was 0.010 V with a 95% confidence interval of (-0.001, 0.021). The mean difference over all visits was 0.011 V. For all patients, the individual threshold differences were within the range of clinical equivalence at all visits. No atrial arrhythmias were observed during 892 ACM tests in 193 patients. Conclusion: This study demonstrated that the ACM algorithm is safe, accurate, and reliable over time. ACM was demonstrated to be clinically equivalent to the manual atrial threshold test in all patients at 1 month and over the entire follow-up period of up to 6 months. ACM ensures atrial capture, may save time during follow-up, and can be used to manage atrial pacing outputs.

Original languageEnglish
Pages (from-to)1203-1210
Number of pages8
JournalHeart rhythm
Issue number11
StatePublished - Nov 2005


  • Atrial capture management
  • Atrial chamber reset
  • Atrial threshold test
  • Atrioventricular conduction
  • Automatic atrial threshold measurement
  • Dual-chamber pacemaker


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