Autologous breast reconstruction in patients with primary hypercoagulability disorders

Nicholas R. Fadell; Kevin He; Adam Boukind; Daehee Jeong; Gary B. Skolnick; Justin M. Sacks; Saif Badran

doi:10.1016/j.bjps.2025.04.034

Autologous breast reconstruction in patients with primary hypercoagulability disorders

Nicholas R. Fadell, Kevin He, Adam Boukind, Daehee Jeong, Gary B. Skolnick, Justin M. Sacks, Saif Badran

Research output: Contribution to journal › Article › peer-review

Abstract

The rising demand for autologous breast reconstruction presents challenges for patients with primary hypercoagulability disorders due to their elevated thrombotic risks. In this article, we reviewed 13 patients who underwent 23 free flap breast reconstructions from 1998 to 2023 with various anticoagulation regimens. Results showed a flap loss rate of 4%, with additional intraoperative and postoperative anticoagulation potentially reducing thrombotic complications. The data concludes that autologous breast reconstruction in hypercoagulable patients is reliable with careful anticoagulation management.

Original language	English
Pages (from-to)	173-176
Number of pages	4
Journal	Journal of Plastic, Reconstructive and Aesthetic Surgery
Volume	105
DOIs	https://doi.org/10.1016/j.bjps.2025.04.034
State	Published - Jun 2025

Keywords

Anticoagulation regimens
Autologous breast reconstruction
DIEP flap
Hypercoagulability
Thrombotic complications

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10.1016/j.bjps.2025.04.034

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title = "Autologous breast reconstruction in patients with primary hypercoagulability disorders",

abstract = "The rising demand for autologous breast reconstruction presents challenges for patients with primary hypercoagulability disorders due to their elevated thrombotic risks. In this article, we reviewed 13 patients who underwent 23 free flap breast reconstructions from 1998 to 2023 with various anticoagulation regimens. Results showed a flap loss rate of 4%, with additional intraoperative and postoperative anticoagulation potentially reducing thrombotic complications. The data concludes that autologous breast reconstruction in hypercoagulable patients is reliable with careful anticoagulation management.",

keywords = "Anticoagulation regimens, Autologous breast reconstruction, DIEP flap, Hypercoagulability, Thrombotic complications",

author = "Fadell, {Nicholas R.} and Kevin He and Adam Boukind and Daehee Jeong and Skolnick, {Gary B.} and Sacks, {Justin M.} and Saif Badran",

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year = "2025",

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doi = "10.1016/j.bjps.2025.04.034",

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AU - Fadell, Nicholas R.

AU - He, Kevin

AU - Boukind, Adam

AU - Jeong, Daehee

AU - Skolnick, Gary B.

AU - Sacks, Justin M.

AU - Badran, Saif

PY - 2025/6

Y1 - 2025/6

N2 - The rising demand for autologous breast reconstruction presents challenges for patients with primary hypercoagulability disorders due to their elevated thrombotic risks. In this article, we reviewed 13 patients who underwent 23 free flap breast reconstructions from 1998 to 2023 with various anticoagulation regimens. Results showed a flap loss rate of 4%, with additional intraoperative and postoperative anticoagulation potentially reducing thrombotic complications. The data concludes that autologous breast reconstruction in hypercoagulable patients is reliable with careful anticoagulation management.

AB - The rising demand for autologous breast reconstruction presents challenges for patients with primary hypercoagulability disorders due to their elevated thrombotic risks. In this article, we reviewed 13 patients who underwent 23 free flap breast reconstructions from 1998 to 2023 with various anticoagulation regimens. Results showed a flap loss rate of 4%, with additional intraoperative and postoperative anticoagulation potentially reducing thrombotic complications. The data concludes that autologous breast reconstruction in hypercoagulable patients is reliable with careful anticoagulation management.

KW - Anticoagulation regimens

KW - Autologous breast reconstruction

KW - DIEP flap

KW - Hypercoagulability

KW - Thrombotic complications

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JO - Journal of Plastic, Reconstructive and Aesthetic Surgery

JF - Journal of Plastic, Reconstructive and Aesthetic Surgery

ER -

Autologous breast reconstruction in patients with primary hypercoagulability disorders

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