Author Correction: Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials (npj Digital Medicine, (2022), 5, 1, (71), 10.1038/s41746-022-00613-w)

NRG Prostate Cancer AI Consortium, Andre Esteva, Jean Feng, Douwe van der Wal, Shih Cheng Huang, Jeffry P. Simko, Sandy DeVries, Emmalyn Chen, Edward M. Schaeffer, Todd M. Morgan, Yilun Sun, Amirata Ghorbani, Nikhil Naik, Dhruv Nathawani, Richard Socher, Jeff M. Michalski, Mack Roach, Thomas M. Pisansky, Jedidiah M. Monson, Farah NazJames Wallace, Michelle J. Ferguson, Jean Paul Bahary, James Zou, Matthew Lungren, Serena Yeung, Ashley E. Ross, Michael Kucharczyk, Luis Souhami, Leslie Ballas, Christopher A. Peters, Sandy Liu, Alexander G. Balogh, Pamela D. Randolph-Jackson, David L. Schwartz, Michael R. Girvigian, Naoyuki G. Saito, Adam Raben, Rachel A. Rabinovitch, Khalil Katato, Howard M. Sandler, Phuoc T. Tran, Daniel E. Spratt, Stephanie Pugh, Felix Y. Feng, Osama Mohamad

Research output: Contribution to journalComment/debate

Abstract

The original version of the published Article contained an error in the description of the prostate tissue samples in the Methods and Results sections, which stated that “pretreatment biopsy samples” and “pretreatment prostate biopsies” were used in this study. Both instances have been updated to “pretreatment and posttreatment prostate tissue”, and these changes are reflected in the HTML and PDF versions of the Article. Furthermore, we have added descriptions of the use of posttreatment prostate tissue during model development throughout the Article. In the interest of transparency and clinical relevance, we repeated the evaluation of model performance in the validation set after removing any cases with post-treatment prostate tissue. This results in a slightly smaller cohort (n = 931) for validation, compared to the 20% validation set used in the original paper, and still demonstrates similar performance to the MMAI algorithms using only pretreatment tissue for each clinical endpoint. Table 2 has been added to the HTML and PDF versions of the Article.

Original languageEnglish
Article number27
Journalnpj Digital Medicine
Volume6
Issue number1
DOIs
StatePublished - Dec 2023

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