The generation of ciliary waveforms requires the spatial and temporal regulation of dyneins. This review catalogues many of the asymmetric structures and proteins in the cilia of Chlamydomonas, a unicellular alga with two cilia that are used for motility in liquid medium. These asymmetries, which have been identified through mutant analysis, cryo-EM tomography and proteomics, provide a wealth of information to use for modelling how waveforms are generated and propagated.
|Journal||Philosophical Transactions of the Royal Society B: Biological Sciences|
|State||Published - Feb 17 2020|
- Cryo-EM tomography
- Dynein arms
- Mutational analysis