Abstract
The generation of ciliary waveforms requires the spatial and temporal regulation of dyneins. This review catalogues many of the asymmetric structures and proteins in the cilia of Chlamydomonas, a unicellular alga with two cilia that are used for motility in liquid medium. These asymmetries, which have been identified through mutant analysis, cryo-EM tomography and proteomics, provide a wealth of information to use for modelling how waveforms are generated and propagated.
Original language | English |
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Article number | 20190153 |
Journal | Philosophical Transactions of the Royal Society B: Biological Sciences |
Volume | 375 |
Issue number | 1792 |
DOIs | |
State | Published - Feb 17 2020 |
Keywords
- Chlamydomonas
- Cryo-EM tomography
- Dynein arms
- Mutational analysis