Brain β-amyloid (Aβ) deposition is a biomarker for Alzheimer's disease (AD) and other dementias, in which Aβ amounts correlate with disease burden. McAlpine et al. reveal that astrocyte expression or administration of interleukin (IL)-3 in the context of aggregated Aβ endows microglia with enhanced capability to cluster and clear Aβ oligomers.

Original languageEnglish
Pages (from-to)937-939
Number of pages3
JournalTrends in Immunology
Issue number11
StatePublished - Nov 2021


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