Associations between physical activity, sedentary behavior, and urinary oxidized guanine in colorectal cancer patients: Results from the colocare study

Richard Viskochil, Biljana Gigic, Tengda Lin, Stephanie Skender, Jürgen Böhm, Petra Schrotz-King, Karen Steindorf, Robert Owen, Jane C. Figueiredo, Christopher I. Li, Erin M. Siegel, Sheetal Hardikar, David Shibata, Adetunji T. Toriola, Martin Schneider, Alexis Ulrich, Cornelia M. Ulrich, Jennifer Ose

Research output: Contribution to journalArticlepeer-review

Abstract

To determine associations between physical activity (PA), sedentary behavior (SB), and oxidative stress in colorectal cancer patients, ColoCare Study participants in Germany wore an accelerometer 6 and/or 12 months after surgery. Spearman partial correlations were used to assess associations between PA and urinary concentrations of oxidized guanine, a validated marker of oxidative stress. There were no significant associations between PA or SB and oxidized guanine in n = 76 measurements (ng/mg creatinine; r = 0.03, p = 0.76 for PA, r = –0.05, p = 0.69 for SB). Novelty • Objectively measured PA was not associated with a marker of oxidative stress in colorectal cancer patients.

Original languageEnglish
Pages (from-to)1306-1309
Number of pages4
JournalApplied Physiology, Nutrition and Metabolism
Volume45
Issue number11
DOIs
StatePublished - 2020

Keywords

  • 8-OHdG
  • Accelerometer
  • Colorectal cancer
  • Oxidative stress
  • Sedentary time

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