Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer

Nicholas R. Lenze, Jeannette T. Bensen, Laura Farnan, Siddharth Sheth, Jose P. Zevallos, Wendell G. Yarbrough, Adam M. Zanation

Research output: Contribution to journalArticlepeer-review

Abstract

Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.

Original languageEnglish
Pages (from-to)412-419
Number of pages8
JournalHead and Neck
Volume44
Issue number2
DOIs
StatePublished - Feb 2022

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