TY - JOUR
T1 - Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer
AU - Lenze, Nicholas R.
AU - Bensen, Jeannette T.
AU - Farnan, Laura
AU - Sheth, Siddharth
AU - Zevallos, Jose P.
AU - Yarbrough, Wendell G.
AU - Zanation, Adam M.
N1 - Publisher Copyright:
© 2021 Wiley Periodicals LLC.
PY - 2022/2
Y1 - 2022/2
N2 - Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.
AB - Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.
UR - http://www.scopus.com/inward/record.url?scp=85119176139&partnerID=8YFLogxK
U2 - 10.1002/hed.26934
DO - 10.1002/hed.26934
M3 - Article
C2 - 34793605
AN - SCOPUS:85119176139
VL - 44
SP - 412
EP - 419
JO - Head & Neck
JF - Head & Neck
SN - 1043-3074
IS - 2
ER -