Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer

Nicholas R. Lenze; Jeannette T. Bensen; Laura Farnan; Siddharth Sheth; Jose P. Zevallos; Wendell G. Yarbrough; Adam M. Zanation

doi:10.1002/hed.26934

Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer

Nicholas R. Lenze, Jeannette T. Bensen, Laura Farnan, Siddharth Sheth, Jose P. Zevallos, Wendell G. Yarbrough, Adam M. Zanation

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.

Original language	English
Pages (from-to)	412-419
Number of pages	8
Journal	Head and Neck
Volume	44
Issue number	2
DOIs	https://doi.org/10.1002/hed.26934
State	Published - Feb 2022

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@article{69d8c3d038084008a59edcced32d55a2,

title = "Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer",

abstract = "Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.",

author = "Lenze, {Nicholas R.} and Bensen, {Jeannette T.} and Laura Farnan and Siddharth Sheth and Zevallos, {Jose P.} and Yarbrough, {Wendell G.} and Zanation, {Adam M.}",

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year = "2022",

month = feb,

doi = "10.1002/hed.26934",

language = "English",

volume = "44",

pages = "412--419",

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issn = "1043-3074",

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TY - JOUR

T1 - Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer

AU - Lenze, Nicholas R.

AU - Bensen, Jeannette T.

AU - Farnan, Laura

AU - Sheth, Siddharth

AU - Zevallos, Jose P.

AU - Yarbrough, Wendell G.

AU - Zanation, Adam M.

PY - 2022/2

Y1 - 2022/2

N2 - Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.

AB - Background: There is a paucity of data on financial toxicity among patients with head and neck squamous cell carcinoma (HNSCC). Materials: This was a retrospective, cross-sectional study of patients with HNSCC surveyed at an outpatient oncology clinic. Results: The sample included 202 patients with HNSCC with a mean age of 59.6 years (SD 10.0). There were 53 patients (26%) with self-reported financial burden. Education of high school or less was a significant predictor of self-reported financial burden (OR 2.52, 95% CI 1.03–6.14, p = 0.042). Patients reporting financial burden had significantly worse physical (p = 0.003), mental (p = 0.003), and functional (p = 0.036) health-related quality of life (HRQOL). Patients reporting financial burden appeared to have lower 5-year overall survival (74.3% vs. 83.9%, p = 0.165), but this association did not reach statistical significance. Conclusion: Financial burden or toxicity may affect approximately a quarter of patients with HNSCC and appears to be associated with worse HRQOL outcomes.

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U2 - 10.1002/hed.26934

DO - 10.1002/hed.26934

M3 - Article

C2 - 34793605

AN - SCOPUS:85119176139

SN - 1043-3074

VL - 44

SP - 412

EP - 419

JO - Head and Neck

JF - Head and Neck

IS - 2

ER -

Association of self-reported financial burden with quality of life and oncologic outcomes in head and neck cancer

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