Association of omental pedicled flap with anastomotic leak following low anterior resection for rectal cancer

Danish Ali, Maria Syed, Adriana C. Gamboa, Alexander T. Hawkins, Scott E. Regenbogen, Jennifer Holder-Murray, Matthew Silviera, Aslam Ejaz, Glen C. Balch, Aimal Khan

Research output: Contribution to journalArticlepeer-review


Background and Objectives: Anastomotic leak following colorectal anastomosis adversely impacts short-term, oncologic, and quality-of-life outcomes. This study aimed to assess the impact of omental pedicled flap (OPF) on anastomotic leak among patients undergoing low anastomotic resection (LAR) for rectal cancer using a multi-institutional database. Methods: Adult rectal cancer patients in the US Rectal Cancer Consortium, who underwent a LAR for stage I–III rectal cancer with or without an OPF were included. Patients with missing data for surgery type and OPF use were excluded from the analysis. The primary outcome was the development of anastomotic leaks. Multivariable logistic regression was used to determine the association. Results: A total of 853 patients met the inclusion criteria and OPF was used in 106 (12.4%) patients. There was no difference in age, sex, or tumor stage of patients who underwent OPF versus those who did not. OPF use was not associated with an anastomotic leak (p = 0.82), or operative blood loss (p = 0.54) but was associated with an increase in the operative duration [β = 21.42 (95% confidence interval = 1.16, 41.67) p = 0.04]. Conclusions: Among patients undergoing LAR for rectal cancer, OPF use was associated with an increase in operative duration without any impact on the rate of anastomotic leak.

Original languageEnglish
Pages (from-to)930-938
Number of pages9
JournalJournal of surgical oncology
Issue number5
StatePublished - Apr 2024


  • anastomotic leak
  • low anastomotic resection
  • omental pedicled flap
  • rectal cancer


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