TY - JOUR
T1 - Association of herpes zoster ophthalmicus with acquired immunodeficiency syndrome and acute retinal necrosis
AU - Sellitti, T. P.
AU - Huang, A. J.W.
AU - Schiffman, J.
AU - Davis, J. L.
N1 - Funding Information:
From the Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Florida. This study was supported in part by grant EY02180 from the National Institutes of Health.
PY - 1993
Y1 - 1993
N2 - We conducted a review to investigate the prevalence of human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome (AIDS), in patients with herpes zoster ophthalmicus, as well as the incidence of acute retinal necrosis after herpes zoster ophthalmicus. All charts of patients seen at our institution between 1987 and 1992 with a primary diagnosis of herpes zoster ophthalmicus were reviewed. Of 112 patients with herpes zoster ophthalmicus, 29 (26%) had HIV or AIDS. All these patients were younger than 50 years at the time of diagnosis. Five of 29 (17%) immunocompromised patients had acute retinal necrosis after herpes zoster ophthalmicus. No acute retinal necrosis was identified in the nonimmunocompromised patients after herpes zoster ophthalmicus. We recommend that all patients younger than 50 years who have herpes zoster ophthalmicus at initial examination be tested for HIV. Additionally, HIV-infected patients should be monitored closely after herpes zoster ophthalmicus for development of acute retinal necrosis. Long-term oral prophylactic as well as initial high-dose intravenous acyclovir may be appropriate in HIV-infected individuals with herpes zoster.
AB - We conducted a review to investigate the prevalence of human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome (AIDS), in patients with herpes zoster ophthalmicus, as well as the incidence of acute retinal necrosis after herpes zoster ophthalmicus. All charts of patients seen at our institution between 1987 and 1992 with a primary diagnosis of herpes zoster ophthalmicus were reviewed. Of 112 patients with herpes zoster ophthalmicus, 29 (26%) had HIV or AIDS. All these patients were younger than 50 years at the time of diagnosis. Five of 29 (17%) immunocompromised patients had acute retinal necrosis after herpes zoster ophthalmicus. No acute retinal necrosis was identified in the nonimmunocompromised patients after herpes zoster ophthalmicus. We recommend that all patients younger than 50 years who have herpes zoster ophthalmicus at initial examination be tested for HIV. Additionally, HIV-infected patients should be monitored closely after herpes zoster ophthalmicus for development of acute retinal necrosis. Long-term oral prophylactic as well as initial high-dose intravenous acyclovir may be appropriate in HIV-infected individuals with herpes zoster.
UR - http://www.scopus.com/inward/record.url?scp=0027164446&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(14)71346-7
DO - 10.1016/S0002-9394(14)71346-7
M3 - Article
C2 - 8357053
AN - SCOPUS:0027164446
SN - 0002-9394
VL - 116
SP - 297
EP - 301
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 3
ER -