Association between new electrocardiographic abnormalities after coronary revascularization and five-year cardiac mortality in BARI randomized and registry patients

Yasuhiro Yokoyama, Bernard R. Chaitman, Regina M. Hardison, Ping Guo, Ronald Krone, Karen Stocke, Ihor Gussak, Michael J. Attubato, Pentti M. Rautaharju, George Sopko, Katherine M. Detre

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

There are few data comparing the relative frequency of new electrocardiographic (ECG) abnormalities after coronary artery bypass grafting (CABG) compared with percutaneous transluminal coronary angioplasty (PTCA) and their association with long-term cardiac mortality. The study population consisted of 3,373 patients who were either randomized or eligible to be randomized to CABG or PTCA in the BARI trial. The frequency of new postprocedural ECG abnormalities was significantly greater after a CABG procedure than after PTCA. The incidence of new postprocedural major Q waves, ST-segment elevation, and T-wave abnormalities were significantly more frequent after CABG. After PTCA (n = 1,869), the 5-year cardiac mortality rates associated with the new development of major Q waves, ST-segment elevation, ST-segment depression, T-wave abnormalities, or no abnormality was 18.1%, 8.5%, 8.9%, 6.0%, and 5.4%, respectively. After CABG (n = 1,427), 5- year cardiac mortality rates were 8.0%, 4.2%, 3.8%, 2.8%, and 3.7%, respectively. The adjusted relative risk of 5-year cardiac mortality for new Q-wave abnormalities was 2.6 after CABG (p<0.04) and 4.6 after PTCA (p<0.01). Thus, patients who undergo CABG have more postinitial procedural ECG abnormalities than patients who undergo PTCA. Cardiac mortality is significantly increased by the new development of postprocedural Minnesota code Q-wave abnormalities regardless of whether patients undergo CABG or PTCA. (C) 2000 by Excerpta Medica, Inc.

Original languageEnglish
Pages (from-to)819-824
Number of pages6
JournalAmerican Journal of Cardiology
Volume86
Issue number8
DOIs
StatePublished - Aug 15 2000

Fingerprint

Dive into the research topics of 'Association between new electrocardiographic abnormalities after coronary revascularization and five-year cardiac mortality in BARI randomized and registry patients'. Together they form a unique fingerprint.

Cite this