Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases

Roland E. Dolle; Jasbir Singh; David Whipple; I. Kelly Osifo; Gary Speier; Todd L. Graybill; Jill S. Gregory; Alex L. Harris; Carla T. Helaszek; Robert E. Miller; Mark A. Ator

doi:10.1021/jm00002a002

Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases

Roland E. Dolle
, Jasbir Singh
, David Whipple
, I. Kelly Osifo
, Gary Speier
, Todd L. Graybill
, Jill S. Gregory
, Alex L. Harris
, Carla T. Helaszek
, Robert E. Miller
, Mark A. Ator

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	220-222
Number of pages	3
Journal	Journal of Medicinal Chemistry
Volume	38
Issue number	2
DOIs	https://doi.org/10.1021/jm00002a002
State	Published - Jan 1 1995

Access to Document

10.1021/jm00002a002

Cite this

Dolle, R. E., Singh, J., Whipple, D., Osifo, I. K., Speier, G., Graybill, T. L., Gregory, J. S., Harris, A. L., Helaszek, C. T., Miller, R. E., & Ator, M. A. (1995). Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases. Journal of Medicinal Chemistry, 38(2), 220-222. https://doi.org/10.1021/jm00002a002

@article{6fc649352018466991e295a11d74a74f,

title = "Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases",

author = "Dolle, \{Roland E.\} and Jasbir Singh and David Whipple and Osifo, \{I. Kelly\} and Gary Speier and Graybill, \{Todd L.\} and Gregory, \{Jill S.\} and Harris, \{Alex L.\} and Helaszek, \{Carla T.\} and Miller, \{Robert E.\} and Ator, \{Mark A.\}",

year = "1995",

month = jan,

day = "1",

doi = "10.1021/jm00002a002",

language = "English",

volume = "38",

pages = "220--222",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

number = "2",

}

Dolle, RE, Singh, J, Whipple, D, Osifo, IK, Speier, G, Graybill, TL, Gregory, JS, Harris, AL, Helaszek, CT, Miller, RE & Ator, MA 1995, 'Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases', Journal of Medicinal Chemistry, vol. 38, no. 2, pp. 220-222. https://doi.org/10.1021/jm00002a002

Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases. / Dolle, Roland E.; Singh, Jasbir; Whipple, David et al.
In: Journal of Medicinal Chemistry, Vol. 38, No. 2, 01.01.1995, p. 220-222.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases

AU - Dolle, Roland E.

AU - Singh, Jasbir

AU - Whipple, David

AU - Osifo, I. Kelly

AU - Speier, Gary

AU - Graybill, Todd L.

AU - Gregory, Jill S.

AU - Harris, Alex L.

AU - Helaszek, Carla T.

AU - Miller, Robert E.

AU - Ator, Mark A.

PY - 1995/1/1

Y1 - 1995/1/1

UR - https://www.scopus.com/pages/publications/0029043446

U2 - 10.1021/jm00002a002

DO - 10.1021/jm00002a002

M3 - Article

C2 - 7830263

AN - SCOPUS:0029043446

SN - 0022-2623

VL - 38

SP - 220

EP - 222

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 2

ER -

Aspartyl α-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1β Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases

Access to Document

Other files and links

Cite this