Arabidopsis: the original plant chassis organism

Cynthia K. Holland, Joseph M. Jez

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

Arabidopsis thaliana (thale cress) has a past, current, and future role in the era of synthetic biology. Arabidopsis is one of the most well-studied plants with a wealth of genomics, genetics, and biochemical resources available for the metabolic engineer and synthetic biologist. Here we discuss the tools and resources that enable the identification of target genes and pathways in Arabidopsis and heterologous expression in this model plant. While there are numerous examples of engineering Arabidopsis for decreased lignin, increased seed oil, increased vitamins, and environmental remediation, this plant has provided biochemical tools for introducing Arabidopsis genes, pathways, and/or regulatory elements into other plants and microorganisms. Arabidopsis is not a vegetative or oilseed crop, but it is as an excellent model chassis for proof-of-concept metabolic engineering and synthetic biology experiments in plants.

Original languageEnglish
Pages (from-to)1359-1366
Number of pages8
JournalPlant Cell Reports
Volume37
Issue number10
DOIs
StatePublished - Oct 1 2018

Keywords

  • Arabidopsis thaliana
  • Chassis organism
  • Genome resources
  • Metabolic engineering
  • Plant biochemistry
  • Synthetic biology

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