TY - JOUR
T1 - Aproximación al conocimiento de las bases genéticas del ictus. Consorcio español de genética del ictus
AU - Giralt-Steinhauer, E.
AU - Jiménez-Conde, J.
AU - Soriano Tárraga, C.
AU - Mola, M.
AU - Rodríguez-Campello, A.
AU - Cuadrado-Godia, E.
AU - Ois, A.
AU - Fernández-Cádenas, I.
AU - Carrera, C.
AU - Montaner, J.
AU - Díaz Navarro, R. M.
AU - Vives-Bauzá, C.
AU - Roquer, J.
N1 - Publisher Copyright:
© 2012 Sociedad Española de Neurología.
PY - 2014
Y1 - 2014
N2 - This article provides an overview of stroke genetics studies ranging from the candidate gene approach to more recent studies by the genome wide association. It highlights the complexity of stroke owing to its different aetiopathogenic mechanisms, the difficulties in studying its genetic component, and the solutions provided to date. The study emphasises the importance of cooperation between the different centres, whether this takes places occasionally or through the creation of lasting consortiums. This strategy is currently essential to the completion of high-quality scientific studies that allow researchers to gain a better knowledge of the genetic component of stroke as it relates to aetiology, treatment, and prevention.
AB - This article provides an overview of stroke genetics studies ranging from the candidate gene approach to more recent studies by the genome wide association. It highlights the complexity of stroke owing to its different aetiopathogenic mechanisms, the difficulties in studying its genetic component, and the solutions provided to date. The study emphasises the importance of cooperation between the different centres, whether this takes places occasionally or through the creation of lasting consortiums. This strategy is currently essential to the completion of high-quality scientific studies that allow researchers to gain a better knowledge of the genetic component of stroke as it relates to aetiology, treatment, and prevention.
KW - Association
KW - Consortium
KW - Genetic risk factors
KW - Genetics
KW - Prediction
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=84922514932&partnerID=8YFLogxK
U2 - 10.1016/j.nrl.2013.04.005
DO - 10.1016/j.nrl.2013.04.005
M3 - Short survey
C2 - 23831412
AN - SCOPUS:84922514932
SN - 0213-4853
VL - 29
SP - 560
EP - 566
JO - Neurologia
JF - Neurologia
IS - 9
ER -