Approaches to oligoribonucleotide synthesis via phosphotriester intermediates

J. H. Van Boom; P. M.J. Burgers; G. R. Owen; C. B. Reese; R. Saffhill

doi:10.1039/C29710000869

Approaches to oligoribonucleotide synthesis via phosphotriester intermediates

J. H. Van Boom, P. M.J. Burgers, G. R. Owen, C. B. Reese, R. Saffhill

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Abstract

Methods are described for the synthesis of uridylyl-(3′ → 5′)-uridine and uridylyl-(3′ → 5′)-uridylyl-(3′ → 5′)-uridine, in good yields a phosphotriester approach has been adopted with the internucleotidic linkages protected by aryl protecting groups.

Original language	English
Pages (from-to)	869-871
Number of pages	3
Journal	Journal of the Chemical Society D: Chemical Communications
Issue number	15
DOIs	https://doi.org/10.1039/C29710000869
State	Published - Jan 1 1971

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title = "Approaches to oligoribonucleotide synthesis via phosphotriester intermediates",

abstract = "Methods are described for the synthesis of uridylyl-(3′ → 5′)-uridine and uridylyl-(3′ → 5′)-uridylyl-(3′ → 5′)-uridine, in good yields a phosphotriester approach has been adopted with the internucleotidic linkages protected by aryl protecting groups.",

author = "{Van Boom}, {J. H.} and Burgers, {P. M.J.} and Owen, {G. R.} and Reese, {C. B.} and R. Saffhill",

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AU - Van Boom, J. H.

AU - Burgers, P. M.J.

AU - Owen, G. R.

AU - Reese, C. B.

AU - Saffhill, R.

PY - 1971/1/1

Y1 - 1971/1/1

N2 - Methods are described for the synthesis of uridylyl-(3′ → 5′)-uridine and uridylyl-(3′ → 5′)-uridylyl-(3′ → 5′)-uridine, in good yields a phosphotriester approach has been adopted with the internucleotidic linkages protected by aryl protecting groups.

AB - Methods are described for the synthesis of uridylyl-(3′ → 5′)-uridine and uridylyl-(3′ → 5′)-uridylyl-(3′ → 5′)-uridine, in good yields a phosphotriester approach has been adopted with the internucleotidic linkages protected by aryl protecting groups.

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AN - SCOPUS:37049142345

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JF - Journal of the Chemical Society, Chemical Communications

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ER -

Approaches to oligoribonucleotide synthesis via phosphotriester intermediates

Abstract

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