Approach to renal biopsy

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The percutaneous kidney biopsy has transformed both the fields of nephrology and pathology. Prior to its introduction in the 1950s, analysis of kidney tissue was available only from deceased autopsy specimens. Advances in technology, technique, and imaging have led to both an improvement in tissue yield in addition to lower morbidity from complications. The kidney biopsy is currently the diagnostic gold standard for nearly all kidney diseases. Although a thorough history and physical in addition to basic serum and urine studies can aid the clinician, the biopsy is oftentimes the next necessary step to confirm a specific diagnosis. Direct sampling of kidney tissue also adds significant prognostic value and can guide management strategies for a variety of disease states. This chapter will outline the history of the kidney biopsy, review tissue adequacy and staining, provide an overview of techniques for native and transplant kidneys along with the associated complications, and discuss future directions and possibilities with this procedure.

Original languageEnglish
Title of host publicationGlomerulonephritis
PublisherSpringer International Publishing
Number of pages15
ISBN (Electronic)9783319493794
ISBN (Print)9783319493787
StatePublished - Feb 26 2019


  • Bleeding complications
  • Kidney biopsy
  • Medical history
  • Nephrology
  • Nephropathology
  • Proteomics
  • Renal biopsy
  • Renal pathology


Dive into the research topics of 'Approach to renal biopsy'. Together they form a unique fingerprint.

Cite this