TY - JOUR
T1 - Applications of nanomedicine in breast cancer detection, imaging, and therapy
AU - Saadeh, Yamaan
AU - Leung, Tiffany
AU - Vyas, Arpita
AU - Chaturvedi, Lakshmi Shankar
AU - Perumal, Omathanu
AU - Vyas, Dinesh
PY - 2014/1
Y1 - 2014/1
N2 - Worldwide, breast cancer remains as one of the most common cancer diagnosis and cause of cancer related death among women. Fortunately, nanomedicine has brought forth new potential and hope in breast cancer research. The extremely small size of nanoparticles makes it advantageous and potentially superior to use in tumor detection and imaging. One of the more extensively studied particles is quantum dots, semiconductor crystals which are capable of enhanced labeling and imaging of cancer cells. In addition, due to serious toxicity of chemotherapeutic agents, nano-formulations of breast cancer chemotherapy are under investigation and development. This may provide easier administering route and reduced frequency of drugs. With the use of nanoparticles, drug delivery can be carried out in a minimally invasive fashion and treatment regimens can be made much more targeted and specific for each patient. In this review article, we provide an overview on the role nanomedicine has played in breast cancer and mention some of the latest diagnostic and treatment modalities researched to date.
AB - Worldwide, breast cancer remains as one of the most common cancer diagnosis and cause of cancer related death among women. Fortunately, nanomedicine has brought forth new potential and hope in breast cancer research. The extremely small size of nanoparticles makes it advantageous and potentially superior to use in tumor detection and imaging. One of the more extensively studied particles is quantum dots, semiconductor crystals which are capable of enhanced labeling and imaging of cancer cells. In addition, due to serious toxicity of chemotherapeutic agents, nano-formulations of breast cancer chemotherapy are under investigation and development. This may provide easier administering route and reduced frequency of drugs. With the use of nanoparticles, drug delivery can be carried out in a minimally invasive fashion and treatment regimens can be made much more targeted and specific for each patient. In this review article, we provide an overview on the role nanomedicine has played in breast cancer and mention some of the latest diagnostic and treatment modalities researched to date.
KW - Breast cancer
KW - Detection
KW - Imaging
KW - Nanomedicine
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=84893802893&partnerID=8YFLogxK
U2 - 10.1166/jnn.2014.8755
DO - 10.1166/jnn.2014.8755
M3 - Review article
C2 - 24730308
AN - SCOPUS:84893802893
SN - 1533-4880
VL - 14
SP - 913
EP - 923
JO - Journal of Nanoscience and Nanotechnology
JF - Journal of Nanoscience and Nanotechnology
IS - 1
ER -