Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β

Robert M. Koffie, Tadafumi Hashimoto, Hwan Ching Tai, Kevin R. Kay, Alberto Serrano-Pozo, Daniel Joyner, Steven Hou, Katherine J. Kopeikina, Matthew P. Frosch, Virginia M. Lee, David M. Holtzman, Bradley T. Hyman, Tara L. Spires-Jones

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Neuroscience