Abstract
Aphasia, was present in a majority of subjects in a longitudinal study of 43 subjects with senile dementia of the Alzheimer type. Aphasic subjects had a more rapidly progressive course but a lower prevalence of familial cases than the study group, other study groups, or the nonaphasic subjects. Conversely, the lack of aphasia was associated with a higher prevalence of familial cases and a slower rate of progression. It is concluded that senile dementia of the Alzheimer type is a heterogeneous disorder in which the presence of aphasia early in the course signifies a nonfamilial, rapidly progressive variety of illness.
Original language | English |
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Pages (from-to) | 255-263 |
Number of pages | 9 |
Journal | Psychiatry Research |
Volume | 14 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1985 |
Keywords
- Alzheimer's disease
- and family history
- aphasia
- dementia