Aortic valve reintervention in patients with failing transcatheter aortic bioprostheses: A statewide experience

Michigan Society of Thoracic and Cardiovascular Surgeons, Blue Cross Blue Shield of Michigan Cardiovascular Consortium, Alex A. Brescia

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Background: Despite the rapid adoption of transcatheter aortic valve replacement since its approval, the frequency and outcomes of aortic valve reintervention after transcatheter aortic valve replacement are poorly understood. Methods: Valve reinterventions, either surgical transcatheter aortic valve explantation or repeat transcatheter aortic valve replacement, between 2012 and 2019 were queried using the Society of Thoracic Surgeons Database and the Transcatheter Valve Therapy Registry through the Michigan Statewide quality collaborative. The reintervention frequency and clinical outcomes including observed-to-expected mortality ratio using Society of Thoracic Surgeons Predicted Risk of Mortality were reviewed. Results: Among 9694 transcatheter aortic valve replacement recipients, a total of 87 patients (0.90%) received a reintervention, consisting of 34 transcatheter aortic valve explants and 53 repeat transcatheter aortic valve replacement procedures. The transcatheter aortic valve explant group demonstrated a higher Society of Thoracic Surgeons Predicted Risk of Mortality. Reintervention cases increased from 0 in 2012 and 2013 to 26 in 2019. The proportion of transcatheter aortic valve explants among all reinterventions increased and was 65% in 2019. Self-expandable devices had a higher reintervention rate than balloon-expandable devices secondary to a higher transcatheter aortic valve explant frequency (0.58% [23/3957] vs 0.19% [11/5737]; P =.001), whereas repeat transcatheter aortic valve replacement rates were similar (0.61% [24/3957] vs 0.51% [29/5737]; P =.51). Among patients with transcatheter aortic valve explants, contraindications to repeat transcatheter aortic valve replacement included unfavorable anatomy (75%), need for other cardiac surgery (29%), other structural issues by transcatheter aortic valve device (18%), and endocarditis (12%). For transcatheter aortic valve explant and repeat transcatheter aortic valve replacement, the 30-day mortality was 15% and 2% (P =.032) and the observed-to-expected mortality ratio was 1.8 and 0.3 (P =.018), respectively. Conclusions: Aortic valve reintervention remains rare but is increasing. The clinical impact of surgical device explantation was substantial, and the proportion of transcatheter aortic valve explants was significantly higher in patients with a self-expandable device.

Original languageEnglish
Pages (from-to)2011-2020.e5
JournalJournal of Thoracic and Cardiovascular Surgery
Volume165
Issue number6
DOIs
StatePublished - Jun 2023

Keywords

  • repeat transcatheter aortic valve replacement
  • surgical aortic valve replacement
  • surgical transcatheter aortic bioprosthesis explantation
  • transcatheter aortic valve replacement

Fingerprint

Dive into the research topics of 'Aortic valve reintervention in patients with failing transcatheter aortic bioprostheses: A statewide experience'. Together they form a unique fingerprint.

Cite this