@article{e926e361843c49c7a30e5fc84cbfaec3,
title = "Antiviral activity of a Rac GEF inhibitor characterized with a sensitive HIV/SIV fusion assay",
abstract = "A virus-dependent fusion assay was utilized to examine the activity of a panel of HIV-1, -2, and SIV isolates of distinct coreceptor phenotypes. This assay allowed identification of entry inhibitors, and characterization of an antagonist of a Rac guanine nucleotide exchange factor, as an inhibitor of HIV-mediated fusion.",
keywords = "Envelope, Fusion, HIV-1, Rac",
author = "Suzanne Pontow and Brooke Harmon and Nancy Campbell and Lee Ratner",
note = "Funding Information: We thank Drs. Joseph Margolick and Homayoon Farzadegan for providing primary isolates from men participating in the Baltimore site of the Multicenter AIDS Cohort Study and acknowledge grants UO1-AI-35042 and 5-MO1-RR-00722 (GCRC). This work was supported by PHS grant AI24745.",
year = "2007",
month = nov,
day = "10",
doi = "10.1016/j.virol.2007.06.022",
language = "English",
volume = "368",
pages = "1--6",
journal = "Virology",
issn = "0042-6822",
number = "1",
}