TY - JOUR
T1 - Antimicrobial resistance in low- and middle-income countries
T2 - current status and future directions
AU - Sulis, Giorgia
AU - Sayood, Sena
AU - Gandra, Sumanth
N1 - Funding Information:
G. Sulis is a former recipient of the David G. Guthrie and the Richard H. Tomlinson Doctoral Fellowships from McGill University. Dr. Sayood is a recipient of the NIH Training Grant n. T32AI007172; the content of this work is solely the responsibility of the author and does not necessarily represent the official views of the National Institutes of Health. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
Publisher Copyright:
© 2021 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - Introduction: Rising rates of antimicrobial resistance (AMR) globally continue to pose agrave threat to human health. Low- and middle-income countries (LMICs) are disproportionately affected, partly due to the high burden of communicable diseases. Areas covered: We reviewed current trends in AMR in LMICs and examined the forces driving AMR in those regions. The state of interventions being undertaken to curb AMR across the developing world are discussed, and the impact of the current COVID-19 pandemic on those efforts is explored. Expert opinion: The dynamics that drive AMR in LMICs are inseparable from the political, economic, socio-cultural, and environmental forces that shape these nations. The COVID-19 pandemic has further exacerbated underlying factors that increase AMR. Some progress is being made in implementing surveillance measures in LMICs, but implementation of concrete measures to meaningfully impact AMR rates must address the underlying structural issues that generate and promote AMR. This, in turn, will require large infrastructural investments and significant political will.
AB - Introduction: Rising rates of antimicrobial resistance (AMR) globally continue to pose agrave threat to human health. Low- and middle-income countries (LMICs) are disproportionately affected, partly due to the high burden of communicable diseases. Areas covered: We reviewed current trends in AMR in LMICs and examined the forces driving AMR in those regions. The state of interventions being undertaken to curb AMR across the developing world are discussed, and the impact of the current COVID-19 pandemic on those efforts is explored. Expert opinion: The dynamics that drive AMR in LMICs are inseparable from the political, economic, socio-cultural, and environmental forces that shape these nations. The COVID-19 pandemic has further exacerbated underlying factors that increase AMR. Some progress is being made in implementing surveillance measures in LMICs, but implementation of concrete measures to meaningfully impact AMR rates must address the underlying structural issues that generate and promote AMR. This, in turn, will require large infrastructural investments and significant political will.
KW - Antibiotic use
KW - Antimicrobial resistance (AMR)
KW - Antimicrobial stewardship
KW - Low- and middle-income countries (LMICs)
KW - Review
UR - http://www.scopus.com/inward/record.url?scp=85110815409&partnerID=8YFLogxK
U2 - 10.1080/14787210.2021.1951705
DO - 10.1080/14787210.2021.1951705
M3 - Article
C2 - 34225545
AN - SCOPUS:85110815409
SN - 1478-7210
VL - 20
SP - 147
EP - 160
JO - Expert Review of Anti-Infective Therapy
JF - Expert Review of Anti-Infective Therapy
IS - 2
ER -