Antimicrobial properties of the constituents of Piper aduncum

Adewole L. Okunade; Charles D. Hufford; Alice M. Clark; David Lentz

doi:10.1002/(SICI)1099-1573(199703)11:2<142::AID-PTR61>3.0.CO;2-Y

Antimicrobial properties of the constituents of Piper aduncum

Adewole L. Okunade
, Charles D. Hufford
, Alice M. Clark
, David Lentz

Division of Nutritional Science & Obesity Medicine

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

An ethanol extract of the leaves of Piper aduncum demonstrated good antimicrobial activity. Bioassay-directed fractionation of this extract led to the isolation of 4-methoxy-3,5-bis(3'-methylbenzoic acid) 1, 2,6-dihydroxy-4-methoxy-chalcone 2, nervogenic acid 3 and 2,2-dimethoxy-8-(3-methyl-2-butenyl)-2H-chromene-6-carboxylic acid 4. These compounds showed considerable in vitro antifungal and antibacterial activity.

Original language	English
Pages (from-to)	142-144
Number of pages	3
Journal	Phytotherapy Research
Volume	11
Issue number	2
DOIs	https://doi.org/10.1002/(SICI)1099-1573(199703)11:2<142::AID-PTR61>3.0.CO;2-Y
State	Published - Mar 1 1997

Keywords

Antifungal prenylated benzoic acid
Antimicrobial
Cahalcone
Chromene derivatives
Piper aduncum

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10.1002/(SICI)1099-1573(199703)11:2<142::AID-PTR61>3.0.CO;2-Y

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title = "Antimicrobial properties of the constituents of Piper aduncum",

abstract = "An ethanol extract of the leaves of Piper aduncum demonstrated good antimicrobial activity. Bioassay-directed fractionation of this extract led to the isolation of 4-methoxy-3,5-bis(3'-methylbenzoic acid) 1, 2,6-dihydroxy-4-methoxy-chalcone 2, nervogenic acid 3 and 2,2-dimethoxy-8-(3-methyl-2-butenyl)-2H-chromene-6-carboxylic acid 4. These compounds showed considerable in vitro antifungal and antibacterial activity.",

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author = "Okunade, \{Adewole L.\} and Hufford, \{Charles D.\} and Clark, \{Alice M.\} and David Lentz",

year = "1997",

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T1 - Antimicrobial properties of the constituents of Piper aduncum

AU - Okunade, Adewole L.

AU - Hufford, Charles D.

AU - Clark, Alice M.

AU - Lentz, David

PY - 1997/3/1

Y1 - 1997/3/1

N2 - An ethanol extract of the leaves of Piper aduncum demonstrated good antimicrobial activity. Bioassay-directed fractionation of this extract led to the isolation of 4-methoxy-3,5-bis(3'-methylbenzoic acid) 1, 2,6-dihydroxy-4-methoxy-chalcone 2, nervogenic acid 3 and 2,2-dimethoxy-8-(3-methyl-2-butenyl)-2H-chromene-6-carboxylic acid 4. These compounds showed considerable in vitro antifungal and antibacterial activity.

AB - An ethanol extract of the leaves of Piper aduncum demonstrated good antimicrobial activity. Bioassay-directed fractionation of this extract led to the isolation of 4-methoxy-3,5-bis(3'-methylbenzoic acid) 1, 2,6-dihydroxy-4-methoxy-chalcone 2, nervogenic acid 3 and 2,2-dimethoxy-8-(3-methyl-2-butenyl)-2H-chromene-6-carboxylic acid 4. These compounds showed considerable in vitro antifungal and antibacterial activity.

KW - Antifungal prenylated benzoic acid

KW - Antimicrobial

KW - Cahalcone

KW - Chromene derivatives

KW - Piper aduncum

UR - https://www.scopus.com/pages/publications/0030946059

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M3 - Article

AN - SCOPUS:0030946059

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VL - 11

SP - 142

EP - 144

JO - Phytotherapy Research

JF - Phytotherapy Research

IS - 2

ER -

Antimicrobial properties of the constituents of Piper aduncum

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Keywords

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