Anticancer Therapy SMRT-ens Up: Targeting the BCL6-SMRT Interaction in B Cell Lymphoma

Leigh A. Compton, Scott W. Hiebert

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

Transcription factors have proven to be difficult targets for the development of small-molecule drugs. In this issue of Cancer Cell, Cerchietti et al. identify and characterize a specific, small-molecule inhibitor of BCL6, an oncogenic transcriptional repressor, that has high clinical promise for treating diffuse large B cell lymphoma.

Original languageEnglish
Pages (from-to)315-316
Number of pages2
JournalCancer Cell
Volume17
Issue number4
DOIs
StatePublished - Apr 13 2010

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