TY - JOUR
T1 - Antibodies in healthcare personnel following severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) infection
AU - Bosserman, Rachel E.
AU - Farnsworth, Christopher W.
AU - O'Neil, Caroline A.
AU - Cass, Candice
AU - Park, Daniel
AU - Ballman, Claire
AU - Wallace, Meghan A.
AU - Struttmann, Emily
AU - Stewart, Henry
AU - Arter, Olivia
AU - Peacock, Kate
AU - Fraser, Victoria J.
AU - Budge, Philip J.
AU - Olsen, Margaret A.
AU - Burnham, Carey Ann D.
AU - Babcock, Hilary M.
AU - Kwon, Jennie H.
N1 - Funding Information:
C.W.F. reports research support from Abbott Laboratories and consulting fees and honoraria from Roche Diagnostics. M.A.O. reports consulting work and grants for an unrelated project from Pfizer. C.A.B. reports receipt of grants from BioFire, bioMerieux, Luminex, and Cepheild and consulting for Pattern, Cepheid, Roche, Beckman Coulter, Accelerate, ThermoFisher, and Bio-Rad Laboratories. C.A.B. has leadership roles with the Journal of Clinical Microbiology, ASM Press, Clinical Chemistry, and Clinical Microbiology Newsletter. C.A.B. has received speaker fees from bioMerieux, Roche, and AACC. All other authors report no potential conflicts.
Funding Information:
This work was supported by the Centers for Disease Control and Prevention (grant no. 5U54CK000482). P.J.B. is supported by from the National Institute of Allergy and Infectious Diseases (grant no. K08AI121422). J.H.K. is supported by the National Institute of Allergy and Infectious Diseases (grant no. 1K23AI137321-01A1).
Publisher Copyright:
© 2022 The Author(s). Published by Cambridge University Press.
PY - 2022/6/15
Y1 - 2022/6/15
N2 - In a prospective cohort of healthcare personnel (HCP), we measured severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) nucleocapsid IgG antibodies after SARS-CoV-2 infection. Among 79 HCP, 68 (86%) were seropositive 14-28 days after their positive PCR test, and 54 (77%) of 70 were seropositive at the 70-180-day follow-up. Many seropositive HCP (95%) experienced an antibody decline by the second visit.
AB - In a prospective cohort of healthcare personnel (HCP), we measured severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) nucleocapsid IgG antibodies after SARS-CoV-2 infection. Among 79 HCP, 68 (86%) were seropositive 14-28 days after their positive PCR test, and 54 (77%) of 70 were seropositive at the 70-180-day follow-up. Many seropositive HCP (95%) experienced an antibody decline by the second visit.
UR - http://www.scopus.com/inward/record.url?scp=85132762609&partnerID=8YFLogxK
U2 - 10.1017/ash.2022.231
DO - 10.1017/ash.2022.231
M3 - Article
C2 - 36483363
AN - SCOPUS:85132762609
SN - 2732-494X
VL - 2
JO - Antimicrobial Stewardship and Healthcare Epidemiology
JF - Antimicrobial Stewardship and Healthcare Epidemiology
IS - 1
M1 - e93
ER -