Anodic oxidation reactions: The total synthesis of (+)-nemorensic acid

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The anodic coupling of an enol ether to an oxygen nucleophile has been used as a key step in the total synthesis of (+)-nemorensic acid. The anodic cyclization reaction allows for a reversal in the way the tetrahydrofuran ring of the natural product is normally assembled and thus enables construction of the ring in a highly stereoselective fashion.

Original languageEnglish
Pages (from-to)7163-7165
Number of pages3
JournalTetrahedron Letters
Issue number41
StatePublished - Oct 8 2001


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