Anodic amide oxidations: Conformationally restricted peptide building blocks from the direct oxidation of dipeptides

Fabrice Cornille, Yvette M. Fobian, Urszula Slomczynska, Denise D. Beusen, Garland R. Marshall, Kevin D. Moeller

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

A pair of bicyclic lactam based conformationally restricted peptide mimetics have been synthesized in good yield by the direct anodic oxidation of dipeptides. This work highlights the simplicity of using electrochemistry to construct peptide mimetics and serves to further define the nature of the substituents that are compatible with an electrochemical procedure for annulating rings onto amino acid derivatives.

Original languageEnglish
Pages (from-to)6989-6992
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number38
DOIs
StatePublished - Sep 19 1994

Fingerprint

Dive into the research topics of 'Anodic amide oxidations: Conformationally restricted peptide building blocks from the direct oxidation of dipeptides'. Together they form a unique fingerprint.

Cite this