Abstract
This comparative review highlights animal models of adrenocortical neoplasia useful either for mechanistic studies or translational research. Three model species-mouse, ferret, and dog-are detailed. The relevance of each of these models to spontaneous and inherited adrenocortical tumors in humans is discussed.
Original language | English |
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Pages (from-to) | 297-310 |
Number of pages | 14 |
Journal | Endocrinology and Metabolism Clinics of North America |
Volume | 44 |
Issue number | 2 |
DOIs | |
State | Published - Jun 1 2015 |
Keywords
- Adrenal cortex
- Cushing syndrome
- Dog
- Endocrine tumor
- Ferret
- Gonadectomy
- Mouse