Abstract

This comparative review highlights animal models of adrenocortical neoplasia useful either for mechanistic studies or translational research. Three model species-mouse, ferret, and dog-are detailed. The relevance of each of these models to spontaneous and inherited adrenocortical tumors in humans is discussed.

Original languageEnglish
Pages (from-to)297-310
Number of pages14
JournalEndocrinology and Metabolism Clinics of North America
Volume44
Issue number2
DOIs
StatePublished - Jun 1 2015

Keywords

  • Adrenal cortex
  • Cushing syndrome
  • Dog
  • Endocrine tumor
  • Ferret
  • Gonadectomy
  • Mouse

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