Angiomyolipoma of the large intestine: Report of a case

Horacio Maluf, Brian Dieckgraefe

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23 Scopus citations


A case of an angiomyolipoma of the large intestine occurring in a 55- year-old man without evidence of tuberous sclerosis is reported. Endoscopically, the lesion resembled a sessile adenomatous polyp. The tumor measured 1 cm. Histologic examination revealed a lesion composed predominantly of spindle and epithelioid cells with significant nuclear atypia. Mitoses were rare. The tumor was strongly positive for HMB-45, CD68, vimentin, desmin, and smooth muscle actin. Rare scattered cells reacted with CD34. No residual tumor was found in the resected colon.

Original languageEnglish
Pages (from-to)1132-1136
Number of pages5
JournalModern Pathology
Issue number12
StatePublished - Dec 1 1999


  • Angiomyolipoma
  • Epithelioid leiomyosarcoma
  • Gastrointestinal stromal tumor
  • HMB-45
  • Large intestine


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