TY - JOUR
T1 - Anatomical evidence for the posterior boundary of area 2 in the macaque monkey
AU - Lewis, James W.
AU - Burton, Harold
AU - Van Essen, David C.
N1 - Funding Information:
We thank Ms Heather Drury for help with the computational flattening of the cortex, and Mrs Shashi Kumar for histological assistance. This work was supported by NIH Grant EY 02091 to D.V.E. and NS 31005 to H.B.
PY - 1999
Y1 - 1999
N2 - This study examined the architectonic organization of the macaque's primary somatosensory cortex near the tip of the intraparietal sulcus (IPS), using myelin and Niss1 stains plus immunohistochemical labeling with the SMI-32 antibody. The surface cortex between the IPS and central sulcus (overlapping area 2) was distinguished from surrounding cortex (areas 1 and 5) by relatively light SMI-32 immunoreactivity. This distinguishing architectonic feature was most evident between the post-central dimple and cortex immediately anterior to the tip of the IPS. Physiological mappings verified that the architectonic transition correlated with a change in receptive field properties, consistent with their marking the boundary between areas 2 and 5. These results suggest that area 2 occupies surface cortex anterior to the IPS, but not within the IPS.
AB - This study examined the architectonic organization of the macaque's primary somatosensory cortex near the tip of the intraparietal sulcus (IPS), using myelin and Niss1 stains plus immunohistochemical labeling with the SMI-32 antibody. The surface cortex between the IPS and central sulcus (overlapping area 2) was distinguished from surrounding cortex (areas 1 and 5) by relatively light SMI-32 immunoreactivity. This distinguishing architectonic feature was most evident between the post-central dimple and cortex immediately anterior to the tip of the IPS. Physiological mappings verified that the architectonic transition correlated with a change in receptive field properties, consistent with their marking the boundary between areas 2 and 5. These results suggest that area 2 occupies surface cortex anterior to the IPS, but not within the IPS.
KW - SMI-32 immunoreactivity
KW - Somatosensory cortex
UR - http://www.scopus.com/inward/record.url?scp=0033404593&partnerID=8YFLogxK
U2 - 10.1080/08990229970438
DO - 10.1080/08990229970438
M3 - Article
C2 - 10632034
AN - SCOPUS:0033404593
SN - 0899-0220
VL - 16
SP - 382
EP - 390
JO - Somatosensory and Motor Research
JF - Somatosensory and Motor Research
IS - 4
ER -