Hepatocellular carcinoma can be diagnosed on a needle biopsy of the liver; however, uncertainty may arise because of the inherent complexity of liver histology. This article aims to provide practicing pathologists with tools for the approach to mass-directed liver biopsies clinically concerning for hepatocellular carcinoma. The examination of routine hematoxylin-eosin stains and the use of ancillary histochemical and immunohistochemical stains are discussed. Sections reviewing liver carcinoma with biphenotypic differentiation and the challenge of dysplastic nodules are included.
|Number of pages||21|
|Journal||Clinics in Liver Disease|
|State||Published - May 1 2015|
- Dysplastic nodule
- Glutamine synthetase
- Hepatocellular carcinoma
- Liver biopsy