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Analysis of modulation of the r1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites
Allison L. Germann
, David E. Reichert
, Ariel B. Burbridge
, Spencer R. Pierce
,
Alex S. Evers
, Joe Henry Steinbach
,
Gustav Akk
Center for the Investigation of Membrane Excitability Diseases
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Division of Pain Research
DBBS - Neurosciences
DBBS - Biochemistry, Biophysics, and Structural Biology
DBBS - Molecular Cell Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
5
Scopus citations
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Dive into the research topics of 'Analysis of modulation of the r1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites'. Together they form a unique fingerprint.
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Keyphrases
Binding Site
100%
Neurosteroids
100%
GABAA Receptor (GABAAR)
100%
Estradiol
50%
Brain Regions
25%
Co-application
25%
Anesthetic Drugs
25%
Retina
25%
Receptor Modulation
25%
Co-agonist
25%
Non-overlapping
25%
Pregnanolone
25%
Carboxylate
25%
Pharmacology
25%
Heteromer
25%
Three-class
25%
Transition Model
25%
Neuroscience
Binding Site
100%
Neurosteroid
100%
GABAA Receptor
100%
Receptor
100%
Diethylstilbestrol
50%
Receptor Modulation
25%
Eltanolone
25%
Brain Region
25%
Biochemistry, Genetics and Molecular Biology
Binding Site
100%
GABAA Receptor
100%
Neurosteroid
100%
Estradiol
50%
Pregnanolone
25%
Sulfate
25%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Neurosteroid
100%
Binding Site
100%
Diethylstilbestrol
22%
Eltanolone
11%
Sulfate
11%