Anal melanoma

Marc Singer, Matthew G. Mutch

Research output: Contribution to journalReview articlepeer-review

64 Scopus citations


Anal melanoma is rare and aggressive malignancy. Patients commonly present with advanced, even metastatic disease. Unlike cutaneous melanoma, anal melanoma has no known risk factors. Surgical excision remains the cornerstone of therapy. There are no long-term survivors of stage II or III disease; therefore, early diagnosis and treatment remain crucial. There are no trials definitively proving abdominal perineal resection (APR) or wide local excision (WLE) to yield superior long-term survival. APR may offer a higher rate of local control, whereas WLE offers a much less morbid operation. Adjuvant chemotherapy, interferon, and radiation may offer some benefit.

Original languageEnglish
Pages (from-to)78-87
Number of pages10
JournalClinics in Colon and Rectal Surgery
Issue number2
StatePublished - May 2006


  • Abdominoperineal resection
  • Anal
  • Malignancy
  • Melanoma
  • Wide local excision


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