TY - JOUR
T1 - An unusual presentation of Richter's transformation of chronic lymphocytic leukemia in liver and lung on18F-labeled fluoro-2-deoxyglucose positron emission tomography/computed tomography
AU - Sood, Apurva
AU - Parihar, Ashwin
AU - Lad, Deepesh
AU - Kumar, Rajender
AU - Singh, Harmandeep
AU - Mittal, Bhagwant
N1 - Publisher Copyright:
© 2019 Indian Journal of Nuclear Medicine | Published by Wolters Kluwer - Medknow.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Richter's transformation (RT) is a rare complication of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) with unfavorable prognosis. The clinical and laboratory findings of RT are nonspecific and requires histopathological confirmation for the diagnosis.18F-labeled fluoro-2-deoxyglucose positron-emission tomography/computed tomography (18F-FDG PET/CT) has shown higher diagnostic values for the detection of transformation of CLL/SLL to aggressive lymphoma. We present a case of CLL in remission for 6 years presenting with clinical features suggestive of RT.18F-FDG PET/CT done in our case showed liver and lung involvement with no lymphadenopathy, which is an unusual presentation of RT.
AB - Richter's transformation (RT) is a rare complication of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) with unfavorable prognosis. The clinical and laboratory findings of RT are nonspecific and requires histopathological confirmation for the diagnosis.18F-labeled fluoro-2-deoxyglucose positron-emission tomography/computed tomography (18F-FDG PET/CT) has shown higher diagnostic values for the detection of transformation of CLL/SLL to aggressive lymphoma. We present a case of CLL in remission for 6 years presenting with clinical features suggestive of RT.18F-FDG PET/CT done in our case showed liver and lung involvement with no lymphadenopathy, which is an unusual presentation of RT.
KW - F-labeled fluoro-2-deoxyglucose positron emission tomography/computed tomography
KW - Richter's transformation
KW - chronic lymphocytic leukemia
KW - liver and lung
UR - http://www.scopus.com/inward/record.url?scp=85077869404&partnerID=8YFLogxK
U2 - 10.4103/ijnm.IJNM_175_19
DO - 10.4103/ijnm.IJNM_175_19
M3 - Article
AN - SCOPUS:85077869404
SN - 0972-3919
VL - 35
SP - 70
EP - 71
JO - Indian Journal of Nuclear Medicine
JF - Indian Journal of Nuclear Medicine
IS - 1
ER -