An unusual pathologic feature associated with dermatomyositis

Jacinda B. Sampson; Steven S. Chin; Frederic C. Clayton; Alan Pestronk; Kathryn J. Swoboda; Kevin M. Flanigan

doi:10.1016/j.nmd.2006.03.013

An unusual pathologic feature associated with dermatomyositis

Jacinda B. Sampson, Steven S. Chin, Frederic C. Clayton, Alan Pestronk, Kathryn J. Swoboda, Kevin M. Flanigan

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We present a case of juvenile dermatomyositis with unusual histopathologic findings. The child presented with a course consistent with dermatomyositis, a diagnosis confirmed by finding reticulotubular aggregates in endothelial cells on electron microscopy. However, histopathology of his muscle biopsy revealed a striking pattern of glycogen accumulation, to an extent similar to that seen in glycogen storage diseases; this degree of accumulation could potentially confound histopathologic diagnosis.

Original language	English
Pages (from-to)	391-393
Number of pages	3
Journal	Neuromuscular Disorders
Volume	16
Issue number	6
DOIs	https://doi.org/10.1016/j.nmd.2006.03.013
State	Published - Jun 2006

Keywords

Anasarca
Glycogen
Myositis
Pediatric dermatomyositis
Reticulotubular aggregates

Access to Document

10.1016/j.nmd.2006.03.013

Cite this

@article{f216b32dad2e4750ae522230d1c6cac7,

title = "An unusual pathologic feature associated with dermatomyositis",

abstract = "We present a case of juvenile dermatomyositis with unusual histopathologic findings. The child presented with a course consistent with dermatomyositis, a diagnosis confirmed by finding reticulotubular aggregates in endothelial cells on electron microscopy. However, histopathology of his muscle biopsy revealed a striking pattern of glycogen accumulation, to an extent similar to that seen in glycogen storage diseases; this degree of accumulation could potentially confound histopathologic diagnosis.",

keywords = "Anasarca, Glycogen, Myositis, Pediatric dermatomyositis, Reticulotubular aggregates",

author = "Sampson, {Jacinda B.} and Chin, {Steven S.} and Clayton, {Frederic C.} and Alan Pestronk and Swoboda, {Kathryn J.} and Flanigan, {Kevin M.}",

year = "2006",

month = jun,

doi = "10.1016/j.nmd.2006.03.013",

language = "English",

volume = "16",

pages = "391--393",

journal = "Neuromuscular Disorders",

issn = "0960-8966",

number = "6",

}

TY - JOUR

T1 - An unusual pathologic feature associated with dermatomyositis

AU - Sampson, Jacinda B.

AU - Chin, Steven S.

AU - Clayton, Frederic C.

AU - Pestronk, Alan

AU - Swoboda, Kathryn J.

AU - Flanigan, Kevin M.

PY - 2006/6

Y1 - 2006/6

N2 - We present a case of juvenile dermatomyositis with unusual histopathologic findings. The child presented with a course consistent with dermatomyositis, a diagnosis confirmed by finding reticulotubular aggregates in endothelial cells on electron microscopy. However, histopathology of his muscle biopsy revealed a striking pattern of glycogen accumulation, to an extent similar to that seen in glycogen storage diseases; this degree of accumulation could potentially confound histopathologic diagnosis.

AB - We present a case of juvenile dermatomyositis with unusual histopathologic findings. The child presented with a course consistent with dermatomyositis, a diagnosis confirmed by finding reticulotubular aggregates in endothelial cells on electron microscopy. However, histopathology of his muscle biopsy revealed a striking pattern of glycogen accumulation, to an extent similar to that seen in glycogen storage diseases; this degree of accumulation could potentially confound histopathologic diagnosis.

KW - Anasarca

KW - Glycogen

KW - Myositis

KW - Pediatric dermatomyositis

KW - Reticulotubular aggregates

UR - http://www.scopus.com/inward/record.url?scp=33744984786&partnerID=8YFLogxK

U2 - 10.1016/j.nmd.2006.03.013

DO - 10.1016/j.nmd.2006.03.013

M3 - Article

C2 - 16697198

AN - SCOPUS:33744984786

SN - 0960-8966

VL - 16

SP - 391

EP - 393

JO - Neuromuscular Disorders

JF - Neuromuscular Disorders

IS - 6

ER -

An unusual pathologic feature associated with dermatomyositis

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this