An introduction to recognizing functional domains

Gary D. Stormo

doi:10.1002/0471250953.bi0201s34

An introduction to recognizing functional domains

Gary D. Stormo

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

This unit provides an overview of issues involved in domain recognition in protein and DNA sequences. It opens with a discussion of the two primary methods of domain representation, namely consensus sequences and alignment matrices (e.g., the log-odds matrix). The unit continues with a brief overview of some of the resources available for identifying functional domains in nucleotide sequences (e.g., transcription factor binding sites). In addition, it reviews databases such as Pfam and InterPro, which are available for protein analysis.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Current Protocols in Bioinformatics
Issue number	SUPPL. 34
DOIs	https://doi.org/10.1002/0471250953.bi0201s34
State	Published - Jun 2011

Keywords

Functional domains
Promoters
Protein domains
Regulatory sites
Transcription factor binding sites

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10.1002/0471250953.bi0201s34

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KW - Promoters

KW - Protein domains

KW - Regulatory sites

KW - Transcription factor binding sites

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An introduction to recognizing functional domains

Abstract

Keywords

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