TY - JOUR
T1 - An Electrocorticographic Brain Interface in an Individual with Tetraplegia
AU - Wang, Wei
AU - Collinger, Jennifer L.
AU - Degenhart, Alan D.
AU - Tyler-Kabara, Elizabeth C.
AU - Schwartz, Andrew B.
AU - Moran, Daniel W.
AU - Weber, Douglas J.
AU - Wodlinger, Brian
AU - Vinjamuri, Ramana K.
AU - Ashmore, Robin C.
AU - Kelly, John W.
AU - Boninger, Michael L.
PY - 2013/2/6
Y1 - 2013/2/6
N2 - Brain-computer interface (BCI) technology aims to help individuals with disability to control assistive devices and reanimate paralyzed limbs. Our study investigated the feasibility of an electrocorticography (ECoG)-based BCI system in an individual with tetraplegia caused by C4 level spinal cord injury. ECoG signals were recorded with a high-density 32-electrode grid over the hand and arm area of the left sensorimotor cortex. The participant was able to voluntarily activate his sensorimotor cortex using attempted movements, with distinct cortical activity patterns for different segments of the upper limb. Using only brain activity, the participant achieved robust control of 3D cursor movement. The ECoG grid was explanted 28 days post-implantation with no adverse effect. This study demonstrates that ECoG signals recorded from the sensorimotor cortex can be used for real-time device control in paralyzed individuals.
AB - Brain-computer interface (BCI) technology aims to help individuals with disability to control assistive devices and reanimate paralyzed limbs. Our study investigated the feasibility of an electrocorticography (ECoG)-based BCI system in an individual with tetraplegia caused by C4 level spinal cord injury. ECoG signals were recorded with a high-density 32-electrode grid over the hand and arm area of the left sensorimotor cortex. The participant was able to voluntarily activate his sensorimotor cortex using attempted movements, with distinct cortical activity patterns for different segments of the upper limb. Using only brain activity, the participant achieved robust control of 3D cursor movement. The ECoG grid was explanted 28 days post-implantation with no adverse effect. This study demonstrates that ECoG signals recorded from the sensorimotor cortex can be used for real-time device control in paralyzed individuals.
UR - http://www.scopus.com/inward/record.url?scp=84873544314&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0055344
DO - 10.1371/journal.pone.0055344
M3 - Article
C2 - 23405137
AN - SCOPUS:84873544314
VL - 8
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 2
M1 - e55344
ER -