TY - GEN
T1 - An efficient algorithm for developing topologically valid matchings
AU - Hanks, Liz
AU - Cytron, Ron K.
AU - Gillett, Will
N1 - Publisher Copyright:
© Springer-Verlag Berlin Heidelberg 1995.
PY - 1995
Y1 - 1995
N2 - We examine a problem that arises in physical DNA mapping, namely determining what common DNA is represented in two maps. We first present an example illustrating the properties of DNA mapping, and present some biological background supporting our approach. We present a new graph structure, called the Z-graph, that takes advantage of structure that develops during the mapping process, thus catalyzing the discovery of all maximum, topologically valid matchings. We describe an algorithm based on this structure and present experimental data supporting its improved performance as compared with a naive approach.
AB - We examine a problem that arises in physical DNA mapping, namely determining what common DNA is represented in two maps. We first present an example illustrating the properties of DNA mapping, and present some biological background supporting our approach. We present a new graph structure, called the Z-graph, that takes advantage of structure that develops during the mapping process, thus catalyzing the discovery of all maximum, topologically valid matchings. We describe an algorithm based on this structure and present experimental data supporting its improved performance as compared with a naive approach.
UR - https://www.scopus.com/pages/publications/84957917017
U2 - 10.1007/3-540-60044-2_40
DO - 10.1007/3-540-60044-2_40
M3 - Conference contribution
AN - SCOPUS:84957917017
SN - 3540600442
SN - 9783540600442
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 144
EP - 161
BT - Combinatorial Pattern Matching - 6th Annual Symposium, CPM 1995, Proceedings
A2 - Galil, Zvi
A2 - Ukkonen, Esko
PB - Springer Verlag
T2 - 6th Annual Symposium on Combinatorial Pattern Matching, CPM 1995
Y2 - 5 July 1995 through 7 July 1995
ER -