An efficient algorithm for developing topologically valid matchings

  • Liz Hanks
  • , Ron K. Cytron
  • , Will Gillett

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We examine a problem that arises in physical DNA mapping, namely determining what common DNA is represented in two maps. We first present an example illustrating the properties of DNA mapping, and present some biological background supporting our approach. We present a new graph structure, called the Z-graph, that takes advantage of structure that develops during the mapping process, thus catalyzing the discovery of all maximum, topologically valid matchings. We describe an algorithm based on this structure and present experimental data supporting its improved performance as compared with a naive approach.

Original languageEnglish
Title of host publicationCombinatorial Pattern Matching - 6th Annual Symposium, CPM 1995, Proceedings
EditorsZvi Galil, Esko Ukkonen
PublisherSpringer Verlag
Pages144-161
Number of pages18
ISBN (Print)3540600442, 9783540600442
DOIs
StatePublished - 1995
Event6th Annual Symposium on Combinatorial Pattern Matching, CPM 1995 - Espoo, Finland
Duration: Jul 5 1995Jul 7 1995

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume937
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference6th Annual Symposium on Combinatorial Pattern Matching, CPM 1995
Country/TerritoryFinland
CityEspoo
Period07/5/9507/7/95

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