An analysis of FDA-approved drugs for oncology

Michael S. Kinch

Research output: Contribution to journalShort surveypeer-review

69 Scopus citations


Cancer remains the second leading cause of death globally. The number of new medicines targeting cancer has grown impressively since the 1990s. On average, ten new drugs are introduced each year. Such growth has partly been achieved by emphasizing biologics and orphan indications, which account for one-quarter and one-half of new oncology drugs, respectively. The biotechnology industry likewise has become the primary driver of cancer drug development in terms of patents, preclinical and clinical research, although pharmaceutical companies are granted more FDA approvals. Many targeting strategies have been successful but recent trends suggest that kinase targets, although tractable, might be overemphasized.

Original languageEnglish
Pages (from-to)1831-1835
Number of pages5
JournalDrug Discovery Today
Issue number12
StatePublished - Dec 2014


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