Amyloid-β ‘seeds’ in old vials of growth hormone

Tien Phat V. Huynh; David M. Holtzman

doi:10.1038/d41586-018-07604-6

Amyloid-β ‘seeds’ in old vials of growth hormone

Tien Phat V. Huynh
, David M. Holtzman

Research output: Contribution to journal › Comment/debate

4 Scopus citations

Abstract

Some samples of human growth hormone used as therapy until the mid-1980s contain amyloid-β peptide and cause genetically modified mice to develop amyloid-β deposits in the brain.

Original language	English
Pages (from-to)	354-355
Number of pages	2
Journal	Nature
Volume	564
Issue number	7736
DOIs	https://doi.org/10.1038/d41586-018-07604-6
State	Published - Dec 20 2018

Keywords

Alzheimer's disease
Neurodegeneration

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10.1038/d41586-018-07604-6

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@article{30aad82723564c87960c9eef58c5d298,

title = "Amyloid-β {\textquoteleft}seeds{\textquoteright} in old vials of growth hormone",

abstract = "Some samples of human growth hormone used as therapy until the mid-1980s contain amyloid-β peptide and cause genetically modified mice to develop amyloid-β deposits in the brain.",

keywords = "Alzheimer's disease, Neurodegeneration",

author = "Huynh, \{Tien Phat V.\} and Holtzman, \{David M.\}",

note = "Publisher Copyright: {\textcopyright} 2018, Nature.",

year = "2018",

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day = "20",

doi = "10.1038/d41586-018-07604-6",

language = "English",

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T1 - Amyloid-β ‘seeds’ in old vials of growth hormone

AU - Huynh, Tien Phat V.

AU - Holtzman, David M.

PY - 2018/12/20

Y1 - 2018/12/20

N2 - Some samples of human growth hormone used as therapy until the mid-1980s contain amyloid-β peptide and cause genetically modified mice to develop amyloid-β deposits in the brain.

AB - Some samples of human growth hormone used as therapy until the mid-1980s contain amyloid-β peptide and cause genetically modified mice to develop amyloid-β deposits in the brain.

KW - Alzheimer's disease

KW - Neurodegeneration

UR - https://www.scopus.com/pages/publications/85058594299

U2 - 10.1038/d41586-018-07604-6

DO - 10.1038/d41586-018-07604-6

M3 - Comment/debate

C2 - 30546137

AN - SCOPUS:85058594299

SN - 0028-0836

VL - 564

SP - 354

EP - 355

JO - Nature

JF - Nature

IS - 7736

ER -

Amyloid-β ‘seeds’ in old vials of growth hormone

Abstract

Keywords

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