Alzheimer disease in 2020

David M. Holtzman; Eckhard Mandelkow; Dennis J. Selkoe

doi:10.1101/cshperspect.a011585

Alzheimer disease in 2020

David M. Holtzman, Eckhard Mandelkow, Dennis J. Selkoe

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105 Scopus citations

Abstract

Remarkable advances in unraveling the biological underpinnings of Alzheimer disease (AD) have occurred during the last 25 years. Despite this, we have made only the smallest of dents in the development of truly disease-modifying treatments. What will change over the next 10 years? While the answer is not clear, we make several predictions on the state of the field in 2020, based on the rich knowledge described in the other contributions in this collection. As such, our predictions represent some of the principal unresolved questions that we believe deserve special investigative attention in the coming decade.

Original language	English
Article number	a011585
Journal	Cold Spring Harbor perspectives in medicine
Volume	2
Issue number	11
DOIs	https://doi.org/10.1101/cshperspect.a011585
State	Published - Nov 2012

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10.1101/cshperspect.a011585

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Alzheimer disease in 2020

Abstract

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