TY - JOUR
T1 - Alterations in pain during adolescence and puberty
AU - Nahman-Averbuch, Hadas
AU - Li, Rui
AU - Boerner, Katelynn E.
AU - Lewis, Christopher
AU - Garwood, Sarah
AU - Palermo, Tonya M.
AU - Jordan, Abbie
N1 - Funding Information:
K.E.B. is supported by a postdoctoral fellowship from the Canadian Child Health Clinician Scientist Program . R.L. is supported by the Center for Child Health, Behavior and Development (CCHBD) Hearst Foundation Fellowship Award at Seattle Children’s Research Institute.
Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2023
Y1 - 2023
N2 - During adolescence and puberty, alterations in pain, both experimental and clinical, are observed. In addition, adolescents undergo extensive biopsychosocial changes as they transition from childhood to adulthood. However, a better understanding of how the biopsychosocial changes during adolescence impact pain is needed to improve pain management and develop targeted pain interventions for adolescents. This review synthesizes the literature on alterations in pain during adolescence in humans, describes the potential biopsychosocial factors impacting pain during adolescence, and suggests future research directions to advance the understanding of the impact of adolescent development on pain.
AB - During adolescence and puberty, alterations in pain, both experimental and clinical, are observed. In addition, adolescents undergo extensive biopsychosocial changes as they transition from childhood to adulthood. However, a better understanding of how the biopsychosocial changes during adolescence impact pain is needed to improve pain management and develop targeted pain interventions for adolescents. This review synthesizes the literature on alterations in pain during adolescence in humans, describes the potential biopsychosocial factors impacting pain during adolescence, and suggests future research directions to advance the understanding of the impact of adolescent development on pain.
KW - biopsychosocial
KW - brain
KW - development
KW - hormones
KW - nociception
KW - sex
UR - http://www.scopus.com/inward/record.url?scp=85148935275&partnerID=8YFLogxK
U2 - 10.1016/j.tins.2023.01.006
DO - 10.1016/j.tins.2023.01.006
M3 - Review article
C2 - 36842946
AN - SCOPUS:85148935275
SN - 0166-2236
JO - Trends in Neurosciences
JF - Trends in Neurosciences
ER -