TY - JOUR
T1 - Allergic rhinitis and asthma
T2 - Celebrating 100 years of immunotherapy
AU - Stokes, Jeffrey R.
AU - Casale, Thomas B.
PY - 2011/12/1
Y1 - 2011/12/1
N2 - Since Noon first described allergen immunotherapy a century ago the basic premise of subcutaneous injections (SCIT) of relevant aeroallergens to induce clinical tolerance has remained true [1]. Indeed, allergen immunotherapy did not change dramatically over the first 75 years, but over the past 25 years there have been a number of important advancements leading to newer approaches and novel formulations. Here we review the top 50 articles published in the past 2 years on allergens, environmental control, and immunotherapy for asthma and allergic rhinitis and the use of immunomodulators in allergic disease.
AB - Since Noon first described allergen immunotherapy a century ago the basic premise of subcutaneous injections (SCIT) of relevant aeroallergens to induce clinical tolerance has remained true [1]. Indeed, allergen immunotherapy did not change dramatically over the first 75 years, but over the past 25 years there have been a number of important advancements leading to newer approaches and novel formulations. Here we review the top 50 articles published in the past 2 years on allergens, environmental control, and immunotherapy for asthma and allergic rhinitis and the use of immunomodulators in allergic disease.
UR - http://www.scopus.com/inward/record.url?scp=82955247942&partnerID=8YFLogxK
U2 - 10.1016/j.coi.2011.07.015
DO - 10.1016/j.coi.2011.07.015
M3 - Review article
C2 - 21862303
AN - SCOPUS:82955247942
SN - 0952-7915
VL - 23
SP - 808
EP - 813
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
IS - 6
ER -