Age-related disparities in older women with breast cancer

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Improvements in breast cancer (BC) mortality rates have not been seen in the older adult community, and the fact that older adults are more likely to die from their cancer than younger women establishes a major health disparity. Studies have identified that despite typically presenting with more favorable histology, older women present with more advanced disease, which may be related in part to delayed diagnosis. This is supported by examination of screening practices in older adults. Older women have a worse prognosis than younger women in both early stage disease, and more advanced and metastatic disease. Focus on the treatment of older adults has often concentrated on avoiding overtreatment, but in fact undertreatment may be one reason for the age-related differences in outcomes, and treatments need to be individualized for every older adult, and take into account patient preferences and functional status and not chronologic age alone. Given the aging population in the US, identifying methods to improve early diagnosis in this population and identify additional factors will be important to reducing this age-related disparity.

Original languageEnglish
Title of host publicationAdvances in Cancer Research
EditorsMarvella E. Ford, Nestor F. Esnaola, Judith D. Salley
PublisherAcademic Press Inc.
Pages23-56
Number of pages34
ISBN (Print)9780128201763
DOIs
StatePublished - 2020

Publication series

NameAdvances in Cancer Research
Volume146
ISSN (Print)0065-230X
ISSN (Electronic)2162-5557

Keywords

  • Breast cancer
  • Cancer disparities
  • Cancer treatment outcomes
  • Geriatric oncology
  • Older adults
  • Post-cancer treatment functional status

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  • Cite this

    Bagegni, N. A., & Peterson, L. L. (2020). Age-related disparities in older women with breast cancer. In M. E. Ford, N. F. Esnaola, & J. D. Salley (Eds.), Advances in Cancer Research (pp. 23-56). (Advances in Cancer Research; Vol. 146). Academic Press Inc.. https://doi.org/10.1016/bs.acr.2020.01.003