Age-related changes in the asthmatic phenotype in children

Caroline C. Horner, Robert C. Strunk

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


PURPOSE OF REVIEW: To review the changes in the asthma phenotype as children progress from childhood into young adulthood. RECENT FINDINGS: Some children with asthma in the early school years improve symptomatically during adolescence and young adulthood, with less frequent remissions and increased relapse rates in those with severe symptoms. During remission of symptoms, lung function abnormalities, airway hyper-responsiveness, and airway inflammation often persist. New data from the Childhood Asthma Management Program cohort show progression of lung function abnormalities during adolescence. SUMMARY: Most children with persistent asthma have persistent disease as adults, and lung function abnormalities continue to progress as these children age.

Original languageEnglish
Pages (from-to)295-299
Number of pages5
JournalCurrent opinion in pediatrics
Issue number3
StatePublished - Jun 1 2007


  • Airway hyper-responsiveness
  • Asthma
  • Lung function
  • Phenotype


Dive into the research topics of 'Age-related changes in the asthmatic phenotype in children'. Together they form a unique fingerprint.

Cite this