@article{f8eaa5ac44c54d37a0dc6c2f5b215f00,
title = "Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses",
abstract = "Memory B cells respond to heterologous antigens either by molding new specificities through secondary germinal centers or by selecting preexisting clones without further affinity maturation. Wong et al. show that for flavivirus challenges, secondary germinal centers minimally contribute to recall responses. Instead, preexisting cross-reactive clones are selected from a diverse memory compartment.",
keywords = "Dengue virus, Japanese Encephalitis virus, West Nile virus, Zika virus, flaviruses, germinal center, memory B cells, plasma cells",
author = "Rachel Wong and Belk, {Julia A.} and Jennifer Govero and Uhrlaub, {Jennifer L.} and Dakota Reinartz and Haiyan Zhao and Errico, {John M.} and Lucas D'Souza and Ripperger, {Tyler J.} and Janko Nikolich-Zugich and Shlomchik, {Mark J.} and Satpathy, {Ansuman T.} and Fremont, {Daved H.} and Diamond, {Michael S.} and Deepta Bhattacharya",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = nov,
day = "17",
doi = "10.1016/j.immuni.2020.09.001",
language = "English",
volume = "53",
pages = "1078--1094.e7",
journal = "Immunity",
issn = "1074-7613",
number = "5",
}