Advanced Neuroimaging for Prevention of Brain Aging

Diana A. Hobbs, Cyrus A. Raji

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Diseases related to brain aging are regularly emerging in elderly populations as life expectancy substantially increases worldwide. The prevalence of obesity is additionally rising, and research shows a relationship exists between obesity and the aging brain. Although these etiologies contribute to the rate at which an individual’s brain starts to show age-related changes, there are a number of lifestyle choices that may be implemented to reduce their impact. Physical activity and diet, lifestyle factors that are highly related to obesity, will be further explored within this chapter. Advancements in neuroimaging have made it possible to identify age-related brain changes and study mechanisms to prevent brain aging. This review focuses on the following magnetic resonance imaging (MRI) techniques: volumetrics, arterial spin labeling (ASL), MR spectroscopy (MRS), diffusion tensor imaging (DTI) and connectivity, and glymphatic imaging.

Original languageEnglish
Title of host publicationHybrid PET/MR Neuroimaging
Subtitle of host publicationA Comprehensive Approach
PublisherSpringer International Publishing
Number of pages9
ISBN (Electronic)9783030823672
ISBN (Print)9783030823665
StatePublished - Jan 1 2021


  • Advanced neuroimaging
  • Aging prevention
  • Alzheimer’s disease
  • Dementia


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